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CB1 RECEPTOR
The CB1 receptors are concentrated in the brain & the central nervous system. CB1 receptors are linked to the endo-cannabinoid anandamide or the phyto-cannabinoid THC.
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CB2 RECEPTORS
The CB2 receptors are mostly found in peripheral organs, especially cells of the immune system. CB2 receptors are related to the endo-cannabinoid 2-AG.
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TRPV1 RECEPTORS
The TRPV1 receptors are concentrated in the blood, bone, marrow, tongue, kidney, liver, stomach and ovaries. These receptors influence temperature and pain.
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TRPV2 RECEPTOR
The TRPV2 receptors are concentrated in the skin, muscles, kidney, stomach and lungs. It mediates cytokine release, phagocytosis, endocytosis, podosome assembly, and inflammation.
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GPR 18 RECEPTOR
The GPR18 receptors can be found primarily in bone marrow, the spleen, lymph nodes, and to a lesser extend in the testes. It mediates in the immune system, and can be compared to an opioid receptor.
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GPR 55 RECEPTOR
The GPR55 receptors are found in bones, the brain, the jejunum and Ileum. GPR55 is expressed in several prostate and ovarian cancer cell lines and has a critical role in regulating proliferation and growth. It is demonstrated to regulate bone cell function.
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GPR 119 RECEPTOR
The GPR119 receptors are found predominantly in the pancreas and the intestinal tract, in small amounts. Activation of the receptor has been shown to cause a reduction in food intake and body weight gain in rats.