Cannabinoids are also chemically produced by pharmaceutical companies. Some of the synthetic cannabis products on the marked are, dronabinol, nabilone, and synthetic CBD. These are CB1 and CB2 receptor ligands, meaning that they act on the same receptors as cannabinoids, but are produced chemically.

There are two types of synthetic cannabinoids. Those are either CBD-derived or THC-derived. The synthetic CBD-derived may be even more effective than natural CBD, and may soon be used in new pharmaceutical drug formulations.

Research in cells and animals has demonstrated that these synthetic cannabinoids can produce similar qualitative physiological, psychoactive, analgesic, anti-inflammatory, and anticancer effects as phyto-cannabinoids. This said, they can be up to 100 times more potent than natural phyto-cannabinoids.